May 3rd, 2021

Children born to obese mothers who follow a dietary and exercise intervention program during pregnancy had a 5 beat per minute reduction in heart rate compared to control children in a large UK study. This change is associated with decreased cardiovascular risk over time in children.

This large trial was not successful in showing a significant reduction in the offspring's fat mass or weight over the three year time frame begging the question of epigenetic changes occurring over generations driving weight gain as has been shown in translational studies.


Dr. M

Dalrymple Pediatric Obesity
Poston Lancet Diabetes and Endocrin
Peacock Int J Env Res Public Health