From the study: Of 1176 patients admitted, 253 had records of a 25(OH)D level prior to COVID-19 infection. A lower vitamin D status was more common in patients with the severe or critical disease (<20 ng/mL) than in individuals with mild or moderate disease (<20 ng/mL). Patients with vitamin D deficiency (<20 ng/mL) were 14 times more likely to have severe or critical disease than patients with 25(OH)D ≥40 ng/mL.

 There have been multiple studies that have shown a correlation between vitamin D deficiency and worse SARS2 Covid 19 outcomes. This is not causation although there are immune mechanisms that make causation possible. The bottom line is that people with obesity and metabolic syndrome have low vitamin D levels in general making the cause likely that which drives metabolic disease. It is well known that obesity is associated with low vitamin D levels which is partly due to fat cells sequestering the fat loving vitamin D from circulation.

Dr. M

Dror PLOSOne