Redo for significance Learning and Memory

 

November 28th, 2021

We have known for a long time that memory is consolidated during the learning process through repetition and associations that provide context to the memory. The chances are that the memory will persist if the associations are strong and the repetition is frequent. Think of your favorite song. You remember the lyrics 20 years later and often a place and event that was associated. In March'sScientific American, we see a full analysis of the mechanisms behind this process that demonstrate the plasticity of this event. 

Read more ...

Breastfeeding part 2

November 28th, 2021

A friend of mine recently told me that she found a 2 year old bottle of refrigerated breastmilk at her house. When she analyzed it, the fat was separated from the watery milk portion. However, there was no gas indicating the presence of large amounts bacteria and no mold visible.

This is not surprising as human breastmilk contains many anti microbial proteins within it. Once sealed, the growth of microbes was minimal as perceived.

Read more ...

Breastmilk is a Miracle of Evolution

November 29th, 2021

After the birth of a child, a beautiful event occurs and provides a point of visceral connection physically and epigenetically between mom and her babe. That event is breastfeeding. Mother’s milk is an evolutionary marvel whereby a mother dedicates part of her energy stores to her offspring for survival. She gives of herself literally and figuratively even during periods of food scarcity. Over thousands of years, humans have evolved this dynamic and rich fluid to promote species

Read more ...

Happy Thanksgiving

 

November 22nd, 2021

Let us look at the silver linings of the pandemic and be grateful for them.

Thanksgiving is always a time to reflect and think about last year. 

Silver linings

1) The pandemic brought families closer together as the loss of business travel has kept many parents home allowing for more connection

2) People began to exercise more with free time setting up a prolonged lifestyle change

Read more ...

Coronavirus Update 49

November 22nd, 2021

North Carolina remains in relative normalcy in most places. The northern states entering winter like conditions are seeing significant increases. Europe is also seeing similar spikes in the colder climate countries.

The next few weeks will show us if wave 5 is truly starting, The good news is that hospitalization and deaths are still uncoupled for the vaccinated individuals as Delta remains the main COVID 19 variant.

Read more ...

Autism Prevalence

November 15th, 2021

The Autism and Developmental Disabilities Monitoring Network is a CDC funded data mining program designed to estimate the number of children with autism spectrum disorders or ASD's.

The network has discovered an estimated prevalence of ASD at 36 out of 1,000 children in most New Jersey regions, but greater than 70 out of 1,000 children in multiple school districts. The national average of ASD is thought to be less than 2 percent.

The authors stated: “When we focused on the district level, we recognized that many communities in our region —approximately one in five, including some of the largest

Read more ...

Air Pollution

November 15th, 2021

We have long known that particulate matter 2.5 is a problem for asthmatic persons. PM 2.5 stands for 2.5 micron sized particles that enter the respiratory tract and settle deep in our lungs smallest tubes. These chemicals cause local inflammation and can lead to further issues over time especially in individuals with lung diseases like COPD or asthma.

Read more ...

Biological Clock and Aging

November 15th, 2021

What do we really know about aging?

We know that it accelerates under chronic unremitting stress of varied sources. Including - chronic high fat and sugar laden westernized diets, chronic chemical or drug exposure or acute if a toxic load, chronic sedentary behavior, chronic metal sadness or abuse, physical abuse, injury that is profound and much more.

It is no wonder looking at that list that we are aging poorly now despite high quality medical interventions that keep us alive.

Read more ...

The calamity of school closures and zoom!

November 8th, 2021

"School closures made up more than one-fourth of all public health interventions in the HIT-COVID database that were implemented from January to June 2020. The right to an accessible and affordable education is protected under article 26 of the UDHR. Epidemiologically, in-person school settings were initially considered a high-risk environment for the spread of COVID-19, but updated data analyses consider them a lower-risk environment regarding for transmission, especially at the elementary school level. School closures have profound consequences for students’ learning, social well-being, and mental health, as well as the ability of parents to work. While various governments have provided virtual education due to in-person school closures, it is not feasible to guarantee quality education or equal access to virtual learning during the pandemic due to inequities in resources (such as internet access) and in parents’ availability to supervise children adequately. Many of these inequities were preexisting and were exacerbated during the pandemic. Thus, this disruption of learning inevitably results in substantial educational gaps for children across the world. The effects of educational gaps have been shown, both historically and currently, to negatively impact learning and life outcomes. A mere three-month school closure could reduce students’ long-term learning by a year, as suggested by modeling simulations. School disruption during World War II was found to be associated with significant income loss 30 years later in life.

School closures also lead to increased prevalence and exacerbation of mental health issues, such as anxiety and depression, among students. School closures place vulnerable children at higher risk of food insecurity, and in many low- and middle-income countries, lack of access to education puts girls in particular at increased risk of child marriage, gender-based violence, sexual assault, and teen pregnancy. For example, the rate of child marriage in Malawi increased by 83% from March to May of 2020 compared to 2019, and the rate of sexual assault, which is linked to child marriage, increased by 151%. Given that child brides are more likely to drop out of school and face gender-based violence, protecting access to education, particularly for girls, should be an imperative in the COVID-19 response, especially in low- and middle-income countries." (Zweig et. al. 2021)

More and more of these net negatives for our children will show up over time. We need to remain hyper vigilant to their needs over the coming years and vow to never repeat this process again.

Dr. M

 

Zweig Health and Human Rights Journal

Section III -

For the Unifying Theory of SARS2/COVID19 pathology that was published in September, please follow this link. In this piece, I lay out what appears to be the pathway to infection and subsequent significant illness. It will be updated in the coming months.

 

Dr. M

 

Volume 11, Letter 47

November 8th, 2021

North Carolina is back to relative normalcy in most places.

If you have had 2 doses of an mRNA vaccine, you have a very very small risk of a significant hospitalization and therefore death from the Delta variant based on statistics overall.

Being Unvaccinated now is the greatest risk factor for a negative outcome. Advancing age and co morbid disease add layers of risk on top of the vaccination status

Read more ...

Flouride Toxicity

November 1st, 2021

More than 80% of fluoride toxicity is seen in children before the age of 6 years, due to ingestion of fluoride-containing toothpaste or mouthwashes (29); it is rare in adults in the developed world. Acute toxicity is characterized by nonspecific gastrointestinal disturbances such as pain, nausea, vomiting, and diarrhea (30,31). In severe cases, this may progress to renal and cardiac dysfunction, coma, and ultimately death (32). In children, as little as 8.4 mg/kg may produce symptoms (30). Chronic fluoride toxicity is usually caused by high fluoride concentrations in drinking water or the use of fluoride supplements.

Read more ...

Scientific Mechanisms for Caries development

November 1st, 2021

The mechanisms of fluoride oral action suggested by Ullah et al. (13) include the following: reduction in de-mineralization of sound enamel by inhibiting microbial growth and metabolism; enhancement of the remineralization and the recovery of demineralized enamel, and the formation of the fluorapatite mineral phase that provides more resistance to demineralization and acid dissolution following acid production by bacteria; inhibition of enzymes such as reduction of immunoglobulin A protease synthesis; reduction in extracellular polysaccharide production which helps in decreasing bacterial adherence to dental hard tissues.

Read more ...

Fluoride

 

November 1st, 2021

What do we know about the state of fluoride need in humans? Do we need it for adequate teeth mineralization? Can we do well without it?

Fluoride is a form of the element fluorine on the periodic table of elements. It is found naturally in rock that over time leaches into water as the primary source of our exposure.

Let us first look at the deficiency state: "In humans, the only clear effect of inadequate fluoride intake is an increased risk of dental caries (tooth decay) for

Read more ...

Visual chart for Vaccination verus unvaccination.

 October 25th, 2021

Interesting visual on the CDC webpage showing vaccination versus unvaccinated death risk during the delta surge. All things equal, being unvaccinated caries an 11 X death risk.

Dr. M

 

CDC Webpage

Volume 11, Letter 45 Coronavirus Update 47

October 25th, 2021

North Carolina is back to relative normalcy in most places.

If you have had 2 doses of an mRNA vaccine, you have a very very small risk of a significant hospitalization and therefore death from the Delta variant based on statistics overall.

Being Unvaccinated now is the greatest risk factor for a negative outcome. Advancing age and co morbid disease add layers of risk on top of the vaccination status

Latest numbers google/CDC

Read more ...

Laboratory animal data related to emulsifiers

October 18th, 2021

Laboratory animal data related to emulsifiers

Taken directly from Encyclopedia of Food Sciences and Nutrition

In Laboratory animals

In laboratory animals colonic damage can be induced experimentally by administration of therapeutic agents. Dogs administered 2.5 mg/kg of the non-steroidal, anti-inflammatory drug indomethecin orally each day for periods of up to 23 days developed not only gastric and small intestinal ulceration but also scattered hemorrhagic erosions in the colon

Read more ...

Emulsifiers

October 18th, 2021

From the Food and Drug Administration: There are thousands of ingredients used to make foods. The Food and Drug Administration (FDA) maintains a list of over 3000 ingredients in its data base "Everything Added to Food in the United States", many of which we use at home every day (e.g., sugar, baking soda, salt, vanilla, yeast, spices and colors). FDA Let us look at emulsifiers.

Emulsifiers

Definition - molecules or chemicals that help maintain a food's even mixture of two or more non mixable foods such as oil and water

Read more ...

  Volume 11, Letter 43 Coronavirus Update 46

 October 11th, 2021

The 4th wave is over in North Carolina.

If you have had 2 doses of an mRNA vaccine, you have a very very small risk of a significant hospitalization and almost no chance of death from the Delta variant based on statistics overall.

Being Unvaccinated now is the greatest risk factor for a negative outcome. Advancing age and co morbid disease add layers of risk on top of the vaccination status

Latest numbers google/CDC

We are continuing to see that the lambda, gamma and mu variants are not an issue yet and likely will not be in the United States as delta is outcompeting them.

Read more ...

It came to me this Morning

As I was sitting outside on the back porch thinking this morning, I came across a memory that meant a lot to me and also predicts a child's outcome to some extent. I once told the story of my childhood musical decision in 3rd grade. My parents ushered me into a large gymnasium at Hagan Elementary School littered with every instrument from the ukulele at one end to the xylophone at the other. When my siblings made the same walk of choice, they chose the violin and the flute respectively.

Then there was little old scrawny 8 year old me. I passed with a huge smile on my face every instrument. "this one?" my father would say. "How about this one?"

Read more ...

A new and interesting book is out: How to raise kids who aren't assholes!

October 4th, 2021

Raising kids is a mix of art and science and likely always will be. In this new book, Melinda Moyer looks at the science side of the equation.

The author writes: "One of the core questions I had was, “How do I raise my kids to be generous and kind?” A lot of what we hear is about the importance of teaching giving and generosity. But the research I kept coming across stemmed from how we talk about feelings. That’s surprising—why would that have anything to do with how generous children would become?

Read more ...